Mining interaction data for biological insights. (A) Circular layout of a map generated by searching the Drosophila Interactions Database for interactions involving 'skp' proteins (colored red). Proteins that interact with two or more Skp proteins are on the circle and were colored green. (B) The map in (A) was redrawn to an 'organic' layout and the edges were colored based on the tables from which the interactions were found. The red edges show interactions found in two or more data sets. (C) The database was searched for proteins that have F-box domains and these were colored blue. Note that a preponderance of the blue nodes can be found in the central group of nodes that interact with two or more Skp proteins.