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Figure 2 | BMC Bioinformatics

Figure 2

From: Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis

Figure 2

The distribution of bit scores as a function of sequence identity. The sequence identity and bit score of each hit when proteins in the interaction data were queried against the rat genome. The solid red line shows the best linear fit to the data and shown in dotted red is a line, starting at the origin, which contains 97% of the data in the area below it. Reading from these lines at 30% sequence identity gives bitscores of 86 and 177, respectively, yielding interaction scores of 9 and 10 when inserted into Equation 1. To ensure a stringent criteria for the minimum interaction score the higher value was selected as a cutoff score.

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