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Table 2 List of genes present in parental left ventricles (LVs) but absent in LV biopsies after microarray analysis. The Pathways (MAPPs) with the highest z-scores in MAPPFinder are given in column one with the related genes in those pathways which disappeared after amplification. Column two gives the Affymetrix Probe IDs of the corresponding genes. In column three the number of LV biopsies in which the gene is absent is given. (Three biopsies were used in the experiment so the maximum number is 3).

From: Biologically relevant effects of mRNA amplification on gene expression profiles

Pathway/ Gene Probe ID # Biopsies (max = 3)
Glycogen Metabolism (12 genes on array; 8 genes changed; 67 %)
Phosphorylase B kinase alpha, muscle 1369357_at 3
Phosphorylase B kinase gamma, muscle 1387445_at 3
Phosphorylase B kinase gamma, testis/liver 1367788_at 3
PP2A, catalytic beta 1387261_at 3
PP2A, B subunit, R5 epsilon 1387485_a_at 2
Glycogen phosphorylase, muscle 1370982_at 1
Phosphoglucomutase 1369473_at 2
Glycogen Synthase Kinase 3 beta 1370267_at 1
Signal transduction of S1P receptor (17 genes on array; 5 genes changed; 29 %)
AKT2 1368832_at 3
G alpha i 1 1387505_at 3
G alpha i 2 1367844_at 1
ERK-1 1387771_a_at 3
ERK-2 1369078_at 3
G protein signaling pathways (50 genes on array; 17 genes changed; 34 %)
G beta 2 1398863_at 3
G beta T2 1398863_at 3
G gamma 3 1373202_at 3
G gamma 5 1398818_at 2
AC2 1367978_at 1
AC4 1368370_at 2
AC5 1368298_at 3
G alpha o 1 1368879_a_at 2
G alpha i 1 1387505_at 3
G alpha i 2 1367844_at 1
PKA 2 alpha reg 1371059_at 3
G alpha 11 1387822_at 2
Phosphatase 2B Catalytic beta 1387261_at 3
PKC gamma 1369089_at 1
PKC eta 1369830_at 3
G alpha 12 1369278_at 2
P115 RhoGEF 1370002_at 3
TGF Beta Signaling Pathway (40 genes on array; 13 genes changed; 30 %)
Betaglycan 1369219_at 3
TbR-I 1369504_at 3
Activin 1369012_at 2
BMP 1387232_at 1
Smad1 1369174_at 3
Smad5 1369276_at 3
Smad7 1368896_at 2
Smad2 1368214_at 1
ERK1 1387771_a_at 3
NF-Kappa-B 1370968_at 1
JNK2 1368646_at 1
Osteopontin 1367581_a_at 3
SIP1 1368229_at 1