Table 4 ORFs and GO terms with highest contributions to the LVs
From: Integrative investigation of metabolic and transcriptomic data
LV | ORFs with significant loadings | Biological Process GO Terms | P-value |
|---|---|---|---|
LV1+ | HXT1, MNT4, HXT3, YER028C, YJL132W, YGL157W, ALD1, ZRT2 | hexose transport | 1.8E-04 |
monosaccharide transport | 1.8E-04 | ||
carbohydrate transport | 5.2E-04 | ||
transport | 7.4E-02 | ||
establishment of localization | 7.7E-02 | ||
LV1- | GSY1, MBR1, ISF1, GDB1, MAL33, QCR8, GLG1, PIG1, YDL157C, CBP4, GPH1, HXK1, GAC1, YPR196W, YLR327C, PRX1, QCR9, PCL7, MAL31, BAP2, INH1, MRK1, YOL053W, YKL187C, YMR103C, MTH1, MCR1, YGR243W, PRS2, ROM1, COX8, COX4, YJR008W, YNL274C, HOR2, COX7, YPL099C, ATP18, QCR10, CNM67, ATP5, ACN9, COX12, COX6 | generation of precursor metabolites and energy | 1.1E-21 |
energy derivation by oxidation of organic compounds | 4.4E-17 | ||
oxidative phosphorylation | 2.0E-13 | ||
electron transport | 1.7E-11 | ||
ATP synthesis coupled electron transport (sensu Eukaryota) | 1.9E-10 | ||
LV2+ | QCR8, PRX1, QCR9, INH1, MCR1, COX8, COX4, COX12, COX6, COX7, ATP18, QCR10, ATP5, AMS1, HAP4, RPM2, PHM8, FBP26, ATP15, YMR034C, YOR220W, TUF1, COR1, ATP3, YNL122C, ATP7, ATP17, ATP20, HXT1, YER028C, YJL132W | oxidative phosphorylation | 2.7E-25 |
generation of precursor metabolites and energy | 5.7E-18 | ||
phosphorylation | 6.0E-18 | ||
phosphorus metabolism | 4.1E-16 | ||
phosphate metabolism | 4.1E-16 | ||
LV2- | PIG1, BAP2, MRK1, PRS2, UBP14, MKC7 | regulation of carbohydrate biosynthesis | 8.1E-05 |
regulation of carbohydrate metabolism | 2.1E-04 | ||
regulation of cellular biosynthesis | 7.4E-04 | ||
regulation of biosynthesis | 7.4E-04 | ||
carbohydrate biosynthesis | 1.2E-03 | ||
LV3+ | PRS2, CBP4, RPL7A, YOR314W, ALD1, ATP5, COX6 | purine ribonucleotide biosynthesis | 5.6E-04 |
purine ribonucleotide metabolism | 6.2E-04 | ||
ribonucleotide biosynthesis | 6.2E-04 | ||
ribonucleotide metabolism | 6.8E-04 | ||
purine nucleotide biosynthesis | 7.1E-04 | ||
LV3- | PIG1, ROM1, CNM67, YBL112C, MSC2, YOL153C, UBI4, RAD2, CHS1, MNT4, ZRT2, PRX1, AMS1, PHM8, FBP26, YMR034C, YOR220W, HXT1, YJL132W | asexual reproduction | 1.9E-02 |
cell budding | 1.9E-02 | ||
carbohydrate metabolism | 1.9E-02 | ||
reproduction | 2.9E-02 | ||
cell homeostasis | 3.4E-02 | ||
LV4+ | MSC2, PRX1, AMS1, PHM8, YMR034C, HXT1, MTH1, YPL099C, TRS23, CYC7, ZRG17, YLR431C, GPG1, YFL034W, PKH1, HXT3, YER028C | monosaccharide transport | 1.2E-05 |
hexose transport | 1.2E-05 | ||
carbohydrate transport | 5.5E-05 | ||
transport | 6.5E-04 | ||
establishment of localization | 7.4E-04 | ||
LV4- | CNM67, MRK1, MKC7, YDL157C, YDR119W, QCR8, QCR9, INH1, COX8, COX4, HAP4, ALD1 | oxidative phosphorylation | 7.6E-09 |
phosphorylation | 5.0E-08 | ||
ATP synthesis coupled electron transport (sensu Eukaryota) | 6.7E-08 | ||
ATP synthesis coupled electron transport | 6.7E-08 | ||
electron transport | 1.6E-07 |