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Table 1 Comparison of the properties of different DNA-microarray simulation models described in literature. '+' and '-' indicate availability of the indicated feature in the specified model. Note that the modeling of features in the specific models is usually not the same.

From: SIMAGE: si mulation of DNA-m icroa rray g ene e xpression data

  Method SIMAGE, this study Lalush et al. [23] Balagurunathan et al. [24] Lonnstedt et al. [25] Wierling et al. [26] GE2
model implementation tabulated gene expression data + - - - - +
  modeling of gene networks - - - - - +
  TIFF output - + + + + -
  software available + [5] + 1 - - - + [27]
  adjustable model + + + + - +/-
model effects background surface pattern + - + - + -
  spot pin / grid effects + + + - - -
  channel effects + - + - - -
  non-linearity effects + - + - - +
  missing data + - + - - -
  'fishtailing' + - + - - +
  spot shape / size - + + - - -
  1. 1) C++ code available from author.