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Table 8 Comparison to other protein disorder predictors over a blind-test set. The non-redundant blind-test set contained 1,304 recent PDB chains that were unrelated to any VSL2 training sequence. The three VSL2 predictors were re-trained with all 1,327 training sequences. The prediction accuracies were calculated at default thresholds, e.g. 0.5 for VL-XT, VL3-E, VSL1, VSL2B, VSL2P and VSL2.

From: Length-dependent prediction of protein intrinsic disorder

  SN SP ACC SN S SN L AUC
VL-XT 56.0 77.9 67.0 55.8 53.0 74.4
VL3-E 28.4 91.4 59.9 26.8 59.7 69.2
DisEMBL 25.9 97.9 61.9 25.7 26.5 83.9
RONN 34.7 88.8 61.8 33.6 56.4 67.2
DISOPRED2 53.8 94.7 74.2 53.5 48.6 84.6
VSL1 75.6 85.8 80.7 76.1 63.6 88.5
VSL2B 73.7 80.8 77.3 74.2 63.1 84.1
VSL2P 78.4 80.4 79.4 78.5 71.6 86.7
VSL2 79.4 81.4 80.4 79.6 73.7 87.5
(a) per-chain
  SN SP ACC SN S SN L AUC
VL-XT 54.2 79.2 66.7 54.7 52.3 74.0
VL3-E 36.5 93.9 65.2 30.5 59.2 75.9
DisEMBL 25.3 98.3 61.8 25.4 24.7 80.1
RONN 41.6 89.1 65.4 39.1 51.2 71.3
DISOPRED2 47.8 95.6 71.7 48.7 44.6 83.4
VSL1 68.3 87.4 77.9 70.9 58.3 86.2
VSL2B 67.1 82.6 74.8 68.9 60.3 82.0
VSL2P 72.7 82.5 77.6 74.2 67.1 85.3
VSL2 74.7 82.8 78.7 76.1 69.4 86.3
(b) per-residue