four sample ROC curves. We group 369 GO functions into four groups based on how informative they are. We say a GO function is more informative if fewer genes are associated with it. H, MH, ML, L denote the 4 groups with high, medium-high, medium-low, and low levels of informativeness. Here, we show sample ROC curves for four randomly selected GO functions, one from each of the four groups. G0:0000002 = "mitochondrial genome maintenance" (from group H); G0:0007568 = "aging" (from group MH); G0:0006626 = "protein targeting to mitochondrion" (from group ML); and G0:0006399 = "tRNA metabolism" (from group L). Solid line = FAM; dashed line = SVM.