Skip to main content

Table 4 averaged cross-validation performance of FAM and SVM for 369 GO functions classified into 4 groups based on how informative they are. A GO function is said to be more informative if fewer numbers of genes are associated with it. N = number of GO functions in each group. H, MH, ML, L denote the 4 groups with high, medium-high, medium-low, and low levels of informativeness. For each GO function, the averaged cross-validation (CV) performance metrics of FAM and SVM are used. These (averaged) CV performance metrics are then averaged over all GO functions within each category. Notice that the last row is identical to that in Table 1.

From: A factor analysis model for functional genomics

   Sensitivity10% Specificity10% AUC
Group N FAM SVM FAM SVM FAM SVM
H 95 0.550 0.532 0.903 0.903 0.788 0.784
MH 144 0.521 0.521 0.904 0.904 0.792 0.790
ML 71 0.449 0.445 0.906 0.906 0.771 0.768
L 59 0.412 0.412 0.908 0.908 0.748 0.749
mean 369 0.497 0.492 0.905 0.905 0.780 0.778