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Figure 9 | BMC Bioinformatics

Figure 9

From: Meta-analysis discovery of tissue-specific DNA sequence motifs from mammalian gene expression data

Figure 9

Statistical significance of known TFs' binding site motifs identified in tissue-specific gene expression clusters. Clusters are depicted as in Figure 8. Shown here is a gradient color scheme, for those motifs that both were found and also passed our block filtering criterion, indicating the significance of the motif matches in terms of standard deviations (SDs) of the log of the group specificity score for that motif match for the given input set of genes, as compared to the mean of the log of the group specificity scores for the size-matched randoms, as indicated in the color bar. Black boxes denote motif matches that were not found, dark gray boxes denote motif matches that were found but that failed block filtering, and light gray boxes denote motif matches that were found and passed block filtering, but whose group specificity scores were not more significant than the geometric mean of the size-matched randoms.

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