From: Meta-analysis discovery of tissue-specific DNA sequence motifs from mammalian gene expression data
(A) Experimentally verified transcription factor binding sites. | |||||
---|---|---|---|---|---|
TF | Known Sites | Wasserman Conserved Sites | 1 kb Upstream Conserved Sites | 2 kb Upstream Conserved Sites | 5 kb Upstream Conserved Sites |
Mef2 | 21 | 16 | 11 | 11 | 11 |
Myf | 24 | 18 | 14 | 14 | 14 |
Sp1 | 24 | 19 | 16 | 16 | 16 |
SRF | 16 | 12 | 10 | 10 | 10 |
Tef | 9 | 9 | 6 | 6 | 6 |
(B) Sites matching PWM. | |||||
TF | Â | Wasserman Conserved Sites | 1 kb Upstream Conserved Sites | 2 kb Upstream Conserved Sites | 5 kb Upstream Conserved Sites |
Mef2 | Â | 25 | 13 | 15 | 17 |
Myf | Â | 78 | 36 | 44 | 91 |
Sp1 | Â | 79 | 43 | 54 | 90 |
SRF | Â | 31 | 22 | 22 | 32 |
Tef | Â | 10 | 7 | 8 | 13 |
(C) Relative enrichment of PWM matches in sequence windows. | |||||
TF | Â | Wasserman Conserved Sites | 1 kb Upstream Conserved Sites | 2 kb Upstream Conserved Sites | 5 kb Upstream Conserved Sites |
Mef2 | Â | 1.00 | 1.16 | 1.00 | 0.57 |
Myf | Â | 1.00 | 1.03 | 0.94 | 0.97 |
Sp1 | Â | 1.00 | 1.21 | 1.14 | 0.95 |
SRF | Â | 1.00 | 1.59 | 1.19 | 0.86 |
Tef | Â | 1.00 | 1.56 | 1.34 | 1.08 |