Screenshot of the TreeSimplifier application. Here, a POU transcription factor tree is compressed to 74 leaves, by treating all species from the Amniota clade as equivalent. On the left, the tree is visualized in a hyperbolic way. On the right, the rule manager panel is shown. It includes a "species replacer rule" that relabels all Amniota species, a "monophylum compressor rule" that uses the NCBI tree modified so that Amniota is a species leaf, and a "paraphylum compressor rule".