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Figure 3 | BMC Bioinformatics

Figure 3

From: Components of the antigen processing and presentation pathway revealed by gene expression microarray analysis following B cell antigen receptor (BCR) stimulation

Figure 3

Internalization of cell surface receptors in WEHI-231. (A-I) Assay for internalization of BCR, CD40, and TLR4 was performed using WEHI-231 cells. Data from 1 hr stimulations are shown. Line thickness represents treatment of cells following labeling of receptor where thin = acid treated samples and thick = no acid treatment. Black = unstimulated, blue = LPS stimulated, red = AIG stimulated, green = anti-CD40 stimulated. Arrow denotes histogram of acid-treated cells in which labeled BCR is protected from the effects of acid treatment with AIG stimulation. (J) Localization of the BCR by fluorescence microscopy. BCR are labeled with a non-stimulating FITC-conjugated monoclonal anti-IgM antibody (green) and treated for 10 minutes as indicated. DIC images are shown in bottom row.

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BMC Bioinformatics

ISSN: 1471-2105

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