Figure 1From: Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stressA. The average value of G(x) at each position in each of the four sets described in the text. Promoter regions in E. coli K12 are generally more destabilized than are either coding or CON regions. The most destabilized site is at position -49 relative to the transcription start site (TSS). B. The Shannon entropy is calculated in promoter-containing regions (blue) and in non- promoter-containing regions (red) for E. coli K12. The -10 regions show a slight increase of sequence conservation relative to other locations.Back to article page