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Table 1 Sequence-to-topology SVM performance using the LRG and PHAT matrices

From: Prediction of amphipathic in-plane membrane anchors in monotopic proteins using a SVM classifier

  No Positional Weighting Positional Weighting  
Substitution Matrix LRGa PHATb LRGc PHATd MLPe
Accuracy 94.0 93.6 93.9 94.3 90.6
Sensitivity 18.3 9.9 28.4 27.2 35.3
Specificity 99.8 100.0 98.9 99.4 94.8
Pnon-IPM 94.1 93.6 94.8 94.7 95.1
PIPM 87.1 94.4 67.0 76.3 34.2
CPM 0.38 0.30 0.41 0.44 0.30
  1. a C = 5.0, 1/2 σ2 = 0.03, window size = 21
  2. b C = 5.0, 1/2 σ2 = 0.01, window size = 21
  3. c C = 25.0, 1/2 σ2 = 0.40, window size = 21 residues
  4. d C = 5.0, 1/2 σ2 = 0.10, window size = 21 residues
  5. e hidden layer size = 16, window size = 15 residues