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Table 3 Quality of the predictions involving multiple alignments. The weights assigned to the aligned sequences are calculated using a BLOSUM weight scheme at a fractional identity of 0.80. LRG and PHAT columns correspond to the substitution matrices used by the SVM.

From: Prediction of amphipathic in-plane membrane anchors in monotopic proteins using a SVM classifier

Substitution Matrix

LRG

PHAT

Accuracy

95.0

95.0

Sensitivity

31.3

31.3

Specificity

99.8

99.8

Pnon-IPM

92.3

93.8

PIPM

95.0

95.0

CPM

0.52

0.53