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Table 3 Quality of the predictions involving multiple alignments. The weights assigned to the aligned sequences are calculated using a BLOSUM weight scheme at a fractional identity of 0.80. LRG and PHAT columns correspond to the substitution matrices used by the SVM.

From: Prediction of amphipathic in-plane membrane anchors in monotopic proteins using a SVM classifier

Substitution Matrix LRG PHAT
Accuracy 95.0 95.0
Sensitivity 31.3 31.3
Specificity 99.8 99.8
Pnon-IPM 92.3 93.8
PIPM 95.0 95.0
CPM 0.52 0.53