TY - JOUR AU - Chen, Feng-Chi AU - Chuang, Trees-Juen PY - 2006 DA - 2006/05/19 TI - The effects of multiple features of alternatively spliced exons on the KA/KSratio test JO - BMC Bioinformatics SP - 259 VL - 7 IS - 1 AB - The evolution of alternatively spliced exons (ASEs) is of primary interest because these exons are suggested to be a major source of functional diversity of proteins. Many exon features have been suggested to affect the evolution of ASEs. However, previous studies have relied on the KA/KSratio test without taking into consideration information sufficiency (i.e., exon length > 75 bp, cross-species divergence > 5%) of the studied exons, leading to potentially biased interpretations. Furthermore, which exon feature dominates the results of the KA/KSratio test and whether multiple exon features have additive effects have remained unexplored. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-7-259 DO - 10.1186/1471-2105-7-259 ID - Chen2006 ER -