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Figure 7 | BMC Bioinformatics

Figure 7

From: Empirical array quality weights in the analysis of microarray data

Figure 7

Estimated versus actual array variance parameters from simulated data. The gene-by-gene update algorithm was used to estimate the array variance parameters using 100, 1000 and 10000 genes from a simulated data set with 10 arrays. The estimates ( γ ^ j MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaiiGacuWFZoWzgaqcamaaBaaaleaacqWGQbGAaeqaaaaa@2FF3@ ) are plotted against the true values (γ j ). As more genes are included in the iterations the accuracy of the estimates obtained from the gene-by-gene update algorithm improve, although with as few as 100 genes, the values recovered are broadly correct.

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