Figure 1From: Spatial normalization of array-CGH dataThe need for an image segmentation method. An array with areas of local spatial bias (bladder cancer data): a straightforward trend correction method does not address the spatial effect appropriately. (a) Median-centered log-ratios; (b) spatial trend; (c) log-ratios after trend subtraction; (d) remaining spatial trend after subtraction (the color scale is not the same as in (b)). Colors are proportional to signal log-ratios; white dots correspond to missing values.Back to article page