TY - JOUR AU - Schultz, Anne-Kathrin AU - Zhang, Ming AU - Leitner, Thomas AU - Kuiken, Carla AU - Korber, Bette AU - Morgenstern, Burkhard AU - Stanke, Mario PY - 2006 DA - 2006/05/22 TI - A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes JO - BMC Bioinformatics SP - 265 VL - 7 IS - 1 AB - Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequence S to the multiple alignment or profile as a whole, S is compared and aligned to individual sequences from A. Within this alignment, S can jump between different sequences from A, so different parts of S can be aligned to different sequences from the input multiple alignment. This approach is particularly useful for dealing with recombination events. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-7-265 DO - 10.1186/1471-2105-7-265 ID - Schultz2006 ER -