Table 3 The numbers of predicted domain interactions using domain fusion, domain function, and combining six data sets. The predicted domain interactions, the number of evidences, and the overlaps with iPfam. Numbers in the first column indicate the number of evidences for the domain interactions, and the second column is the number of interactions having the corresponding evidences. "PPI" represents the protein interaction data sets. "Fraction" indicates the fraction of domain interactions in iPfam in a given set. "Fold" indicates the ratio of the fraction over expected value (0.17%).
From: An integrated approach to the prediction of domain-domain interactions
Evidence | Interactions | Overlap with iPfam | Fraction | Fold |
|---|---|---|---|---|
Random domain pairs | 1,539,135 | 2,580 | 0.17% | - |
Domain fusion | 9,615 | 1,141 | 11.8% | 69 |
Domain fusion & PPI | 859 | 283 | 32.9% | 194 |
Same GO terms | 57,907 | 1,302 | 0.8% | 13 |
Same GO terms & PPI | 1,031 | 234 | 22.7% | 134 |
≥ 1 | 23,606 | 2,071 | 8.8% | 52 |
≥ 2 | 1,624 | 820 | 50.5% | 297 |
≥ 3 | 307 | 200 | 65.1% | 383 |
≥ 4 | 58 | 43 | 74.1% | 436 |
≥ 5 | 13 | 10 | 76.9% | 452 |
= 6 | 0 | - | - | - |