TY - JOUR AU - Okoniewski, MichaƂ J. AU - Miller, Crispin J. PY - 2006 DA - 2006/06/02 TI - Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations JO - BMC Bioinformatics SP - 276 VL - 7 IS - 1 AB - Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship between probes and targets and used to make inferences about transcript- and, ultimately, gene expression. In some situations, a probe is capable of hybridizing to more than one transcript, in others, multiple probes can target a single sequence. These 'multiply targeted' probes can result in non-independence between measured expression levels. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-7-276 DO - 10.1186/1471-2105-7-276 ID - Okoniewski2006 ER -