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Figure 5 | BMC Bioinformatics

Figure 5

From: EVEREST: automatic identification and classification of protein domains in all protein sequences

Figure 5

Performance of EVEREST release 1, ProtoNet and ADDA with respect to Pfam and SCOP. A. Accuracy with respect to Pfam. Histogram of scores of EVEREST/ProtoNet/ADDA families with respect to best matching Pfam families. B. Coverage of non-trivial Pfam families: Histogram over non-trivial Pfam families, of scores of best matching EVEREST/ProtoNet/ADDA families. C. Coverage of hetero Pfam families: Histogram over hetero Pfam families, of scores of best matching EVEREST/ProtoNet/ADDA families. D, E, F: As A, B, C, with SCOP in place of Pfam. G. EVEREST Accuracy w.r.t Pfam: Two-dimensional histogram of sensitivity and selectivity of EVEREST families with respect to best matching Pfam families. H. EVEREST Coverage of hetero Pfam: Two-dimensional histogram over hetero Pfam families, of sensitivity and selectivity of best matching EVEREST families. I, J: As G, H, with SCOP in place of Pfam. Bins count values above lower threshold, and below or equal to upper threshold (for coverage, Pfam/SCOP families that are not intersected by any EVEREST (ProtoNet/ADDA) family are added to the lowest bin). In G, H, I and J, numbers are percentages of families in bin. See sections Evaluation of Classification and Evaluating a Suggested Domain Family for further details.

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