Table 1 Performance of EVEREST release 1, ProtoNet and ADDA with respect to Pfam
From: EVEREST: automatic identification and classification of protein domains in all protein sequences
Thresholds | Accuracy | Hetero Family Coverage | |||||||
|---|---|---|---|---|---|---|---|---|---|
Selectivity | Sensitivity | EVEREST | ProtoNet | ADDA | EVEREST | ProtoNet | ADDA | ||
| Â | Â | Â | Â | Â | All | Train | Test | Â | Â |
50% | 50% | 62% | 32% | 25% | 71% | 71% | 72% | 41% | 53% |
50% | 75% | 52% | 27% | 22% | 66% | 65% | 66% | 35% | 45% |
50% | 87.5% | 42% | 24% | 20% | 59% | 58% | 59% | 29% | 39% |
50% | 93.75% | 35% | 23% | 19% | 52% | 52% | 52% | 25% | 35% |
75% | 50% | 51% | 27% | 23% | 65% | 65% | 65% | 24% | 42% |
75% | 75% | 43% | 23% | 20% | 60% | 59% | 60% | 19% | 34% |
75% | 87.5% | 35% | 21% | 18% | 52% | 52% | 53% | 14% | 29% |
75% | 93.75% | 29% | 19% | 18% | 46% | 46% | 46% | 11% | 26% |
87.5% | 50% | 43% | 26% | 23% | 60% | 60% | 59% | 19% | 38% |
87.5% | 75% | 36% | 21% | 19% | 55% | 56% | 54% | 14% | 31% |
87.5% | 87.5% | 30% | 19% | 18% | 48% | 49% | 47% | 10% | 26% |
87.5% | 93.75% | 24% | 18% | 17% | 42% | 43% | 41% | 07% | 23% |
93.75% | 50% | 37% | 25% | 22% | 55% | 56% | 54% | 16% | 34% |
93.75% | 75% | 31% | 21% | 19% | 50% | 51% | 50% | 11% | 27% |
93.75% | 87.5% | 26% | 19% | 18% | 44% | 44% | 44% | 07% | 23% |
93.75% | 93.75% | 21% | 18% | 17% | 38% | 39% | 37% | 05% | 21% |