Table 1 Fraction of multi-functional fold families in the SCOP database. About half of the protein domains belong to a multi-functional fold family, suggesting that the problem of ambiguous functional assignment is very common for experimental structures.
From: Automated functional classification of experimental and predicted protein structures
Category | Number of folds | Number of superfamilies | Number of families | Number of domains |
|---|---|---|---|---|
Folds with multiple superfamilies | 127 | 755 | 1,414 | 32,913 |
Folds with a single superfamily | 1,006 | 1,006 | 1,700 | 37,946 |