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Table 3 Performance of MCALIGN2(DP), MCALIGN(MC) and PairHMM_KM compared by examining the proportions of correctly aligned sites.

From: MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution

Simulated

Proportions of correctly aligned sites.

t

Θ

PAIRHMM

MC

DP

0.05

0.225

0.992 (0.0072)

0.992 (0.0078)

0.993 (0.0074)

0.10

0.225

0.977 (0.0133)

0.977 (0.0137)

0.977 (0.0127)

0.15

0.225

0.954 (0.0210)

0.951 (0.0235)

0.955 (0.0186)

0.20

0.225

0.920 (0.0300)

0.915 (0.0345)

0.922 (0.0293)

0.25

0.225

0.868 (0.0416)

0.850 (0.0596)

0.869 (0.0433)

0.30

0.225

0.810 (0.0500)

0.761 (0.0853)

0.813 (0.0511)

0.15

0.10

0.984 (0.0116)

0.983 (0.0102)

0.983 (0.0108)

0.15

0.30

0.933 (0.0224)

0.925 (0.0292)

0.933 (0.0246)

0.15

0.40

0.905 (0.0325)

0.894 (0.0376)

0.906 (0.0329)

  1. Proportion of matched bases from 200 replicates for each combination of t and θ, with sequences of length 500 base pairs. Standard deviation of mean is shown after the proportion of matched bases in parentheses.