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Figure 1 | BMC Bioinformatics

Figure 1

From: WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data

Figure 1

Overview of WholePathwayScope (WPS): schematic work flow for WPS basic data and file processing. WPS imports the data from the microarray file to the criteria (CRI) file, from which gene lists can be obtained by pattern extraction and then subjected to statistical evaluation by Fisher's exact test or to generate a GTAN. The GenBank IDs of genes in microarray datasets and pathway files (PSCP and WSCP files) are mapped to BaseGenBankIDs. The user then sets the criteria by which the gene tags and pathway tags in the PSCP and WSCP files are to be colored. PathwayScope Files (PSCP) including the GTAN (gene-term association network) files and WholeScope Files (WSCP) are either provided or created by the user. WPS integrates the data from the CRI files with the PSCP and WSCP files so that genes and pathways are flagged according to the specifications of the user.

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