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Figure 3 | BMC Bioinformatics

Figure 3

From: WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data

Figure 3

An example of WSCP files in which multiple microarray datasets were analyzed simultaneously. A WSCP file that included a collection of metabolic pathways and gene families with relevance to lipid and glucose metabolism was analyzed using data from the five different microarray datasets (see Additional file 11 for description of material and data preparation). Pooled hepatic mRNA isolated from two sets of G 5G 8Tg mice (G5G8Tg1Liver, G5G8Tg2Liver) and three sets of G 5G 8 knockout mice (G5G8-/-1Liver, G5G8-/-2Liver, G5G8-/-3Liver) were hybridized to Affymetrix chips. Each pathway tag is divided into boxes that are tandemly arrayed in the same order as shown at the top of the figure. Once the data is loaded from each of the experiments, the boxes are colored according to the criteria set by the user. The numbers displayed next to the pathway tags (or divided boxes) are numbers of genes matched with pathway criteria-based gene criteria. (Note: if a single CRI is loaded, the whole pathway tag will be colored by this CRI).

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