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Table 1 An example of gene criteria for the microarray dataset for G5G8 Tg mice vs wild-type mice.

From: WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data

Criteria Priority

Criteria Name

Criteria Details

Color

1

UpHighCertainty

([TGvsWT_A_Change] = 'I' OR [TGvsWT_A_Change] = 'MI')AND ([WT_A_Detection] <> 'A' OR [TGvsWT_A_Detection] <> 'A')

red

2

DownHighCertainty

[TGvsWT_A_Change] = 'D' OR [TGvsWT_A_Change] = 'MD') AND ([WT_A_Detection] <> 'A' OR [TGvsWT_A_Detection] <> 'A')

green

3

UpLowCertainty

[foldchange] >= 2

orange

4

DownLowCertainty

[foldchange] < = 0.5

light blue

5

No Criteria Met

Program built-in criteria (all of the above criteria not met)

gray

6

Not Found

Gene does not exist in microarray dataset

white

  1. [TGvsWT_A_Change]: Change call of Affymetrix array for genes in Transgene array in compared to Wild type array (I: Increase; D: Derease; MI: Medium Increase; MD: Medium Decrease)
  2. [WT_A_Detection]: Detection Call of Affymetrix array for Wild Type array (A: absent, P: present).
  3. [TGvsWT_A_Detection]: Detection Call of Affymetrix array for G5G8Tg array (A: absent; P: present).