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Table 7 Reflected bias. The estimated reflected bias of the DE-genes as defined in Relation 2. A reflected bias equal to -1 implies that only 50% of the true regulation was observed.

From: Evaluation of microarray data normalization procedures using spike-in experiments

Scanning procedure

Censuring value

Procedure

  

Complete filtration

Partial filtration

No filtration

  

No ba

Ba

No ba

Ba

No ba

Ba

Ba+C

  

I

II

IV

V

VII

VIII

IX

70 scan

1

-1.3

0.0

-1.4

-0.4

-1.5

-0.2

-0.4

 

8

 

-0.3

 

-0.7

 

-0.4

-0.6

 

64

 

-1.2

 

-1.4

 

-1.3

-1.4

 

512

 

-2.2

 

-2.2

 

-2.2

-2.2

80 scan

1

-0.8

-0.2

-1.0

-0.6

-1.0

-0.4

-0.4

 

8

 

-0.3

 

-0.6

 

-0.4

-0.4

 

64

 

-0.5

 

-0.8

 

-0.7

-0.7

 

512

 

-1.4

 

-1.5

 

-1.5

-1.5

90 scan

1

-0.9

-0.5

-1.0

-0.7

-1.0

-0.6

-0.6

 

8

 

-0.5

 

-0.7

 

-0.6

-0.6

 

64

 

-0.5

 

-0.8

 

-0.6

-0.6

 

512

 

-0.8

 

-1.0

 

-0.9

-1.0

100 scan

1

-1.3

-0.9

-1.4

-1.1

-1.4

-1.0

-1.0

 

8

 

-0.9

 

-1.1

 

-1.0

-1.0

 

64

 

-0.9

 

-1.1

 

-1.0

-1.0

 

512

 

-0.9

 

-1.1

 

-1.1

-1.1

RLS 90

1

-0.9

-0.5

-1.0

-0.7

-1.0

-0.6

-0.6

 

8

 

-0.5

 

-0.7

 

-0.6

-0.6

 

64

 

-0.5

 

-0.7

 

-0.6

-0.6

 

512

 

-0.8

 

-1.0

 

-0.9

-0.9

RLS 100

1

-1.0

-0.5

-1.1

-0.7

-1.1

-0.6

-0.6

 

8

 

-0.5

 

-0.7

 

-0.6

-0.6

 

64

 

-0.5

 

-0.7

 

-0.6

-0.6

 

512

 

-0.5

 

-0.8

 

-0.7

-0.7

CM

1

-1.0

-0.8

-1.1

-1.0

-1.1

-0.7

-0.7

 

8

 

-0.9

 

-1.0

 

-0.8

-0.8

 

64

 

-1.4

 

-1.5

 

-1.5

-1.5

 

512

 

-2.2

 

-2.2

 

-2.2

-2.2