Figure 1
From: Improving the accuracy of protein secondary structure prediction using structural alignment
A) Flow chart outlining how protein sequences are processed by PROTEUS. Each query sequence is simultaneously processed through PROTEUS' three de novo predictors (lower left corner) and through a BLAST comparison and global alignment (via XALIGN) against the PDB, to yield a 3D-to-2D mapping. The two secondary structure predictions are merged and filtered to produce a final consensus prediction. B) Detail illustrating how the two predictions are merged in the final processing step.