Table 1 Frequency of 4- or 5-nucleotide motifs in the 5' upstream regions of the ORFs as compared to the complete genome for the viruses Ac MNPV, HHV1, Vaccinia virus, ASFV and WSSV. Only the 15 motifs with the highest relative enrichment are shown for each virus. For Ac MNPV, HHV1 and WSSV, sequences that are part of the consensus TATA box (TATA(a/t)A) are underlined, while for Vaccinia virus and ASFV sequences only consisting of A and T residues are italics. * Means P ≤ 0.05

taag^c

393

(29)

90

(114)

4.0*

taag^c

393

(29)

137

(87)

3.0*

tata

1314

(66)

172

(149)

2.3*

tata

1314

(66)

255

(111)

1.7*

ataa

1973

(101)

222

(198)

1.9*

ataa

1973

(101)

363

(162)

1.6*

atat

1616

(81)

170

(147)

1.8*

atat

1616

(81)

268

(116)

1.4*

agta

671

(49)

70

(89)

1.8*

agta

671

(49)

109

(69)

1.4*

aagg

473

(51)

41

(76)

1.5

gata^d

867

(63)

137

(87)

1.4

gata^d

867

(63)

74

(94)

1.5

aata

2230

(115)

346

(154)

1.3

cact^e

612

(64)

52

(95)

1.5

cagt^f

698

(73)

106

(96)

1.3

aata

2230

(115)

186

(166)

1.4

ctta

393

(28)

59

(37)

1.3

atta

1957

(98)

163

(141)

1.4

tcac^e

669

(70)

99

(90)

1.3

gtat

949

(68)

79

(98)

1.4

gcta

541

(57)

77

(70)

1.2

cagt^f

698

(73)

58

(105)

1.4

cccc

190

(42)

27

(52)

1.2

taaa

2716

(140)

222

(198)

1.4

tacc

444

(47)

63

(57)

1.2

aggg

233

(35)

19

(50)

1.4

tagt

737

(53)

104

(64)

1.2

tagt

737

(53)

58

(72)

1.4

cact^e

612

(64)

86

(78)

1.2

HHV1

ttag

221

(53)

17

(168)

3.2*

ataa

372

(192)

42

(445)

2.3*

ctag

182

(20)

13

(60)

2.9*

tata

306

(159)

32

(342)

2.2*

ctct

658

(76)

38

(180)

2.4*

ctag

182

(20)

19

(44)

2.1*

tagc

365

(41)

21

(97)

2.4*

taaa

454

(234)

47

(498)

2.1*

tcta

199

(49)

11

(111)

2.3*

catt^g

339

(83)

35

(176)

2.1*

tttt

807

(426)

44

(955)

2.2*

taag

254

(60)

26

(127)

2.1*

tagg

342

(38)

17

(77)

2.0*

ttaa

356

(185)

35

(374)

2.0*

cata

369

(90)

18

(180)

2.0*

ctct

658

(76)

64

(152)

2.0*

ctta

254

(62)

12

(121)

1.9*

ttag

221

(53)

21

(104)

2.0*

ccta

342

(39)

16

(75)

1.9

cata

369

(90)

34

(170)

1.9*

tctc

892

(103)

41

(194)

1.9

ctta

254

(62)

23

(116)

1.9*

ctgt

936

(106)

40

(186)

1.8

tttt

807

(426)

72

(782)

1.8*

ctac

492

(56)

21

(99)

1.8

cctt

795

(92)

68

(161)

1.8

ttcc

990

(114)

42

(199)

1.7

aaat

324

(167)

27

(286)

1.7

cact

433

(50)

18

(85)

1.7

ctat

242

(59)

20

(101)

1.7

Vaccinia virus

taaa ^h

4421

(94)

472

(140)

1.5*

gcac

391

(66)

77

(91)

1.4*

aaaa ^h

5439

(115)

564

(167)

1.5*

ataa

4528

(96)

822

(122)

1.3*

ataa

4528

(96)

446

(133)

1.4*

taaa ^h

4421

(94)

796

(118)

1.3*

aaat ^h

4454

(94)

432

(128)

1.4*

tact

2010

(85)

353

(105)

1.2*

cgcg

318

(107)

30

(141)

1.3*

acta

2179

(92)

373

(111)

1.2*

gggg

171

(57)

16

(75)

1.3*

aaat ^h

4454

(94)

755

(112)

1.2

acac

1112

(94)

103

(122)

1.3*

aaaa ^h

5439

(115)

911

(135)

1.2

aata

5203

(110)

479

(142)

1.3*

tgca

832

(70)

138

(82)

1.2

ttaa

3720

(79)

337

(100)

1.3

aata

5203

(110)

857

(127)

1.2

tact

2010

(85)

179

(106)

1.3

ctac

1264

(107)

208

(123)

1.2

acta

2179

(92)

190

(113)

1.2

gccg

384

(129)

63

(148)

1.2

tata

4748

(101)

411

(122)

1.2

gcga

500

(84)

82

(97)

1.2

tgaa

1917

(81)

165

(98)

1.2

cacg

586

(98)

96

(113)

1.2

ctaa

1830

(77)

157

(93)

1.2

accc

403

(68)

66

(78)

1.2

gtaa

1921

(81)

164

(97)

1.2

cata

2186

(92)

358

(106)

1.2

ASFV

tata ⁱ

2686

(91)

261

(199)

2.2*

tata ⁱ

2686

(91)

405

(154)

1.7*

ataa

3146

(107)

278

(214)

2.0*

ataa

3146

(107)

432

(166)

1.5*

aatt

2634

(89)

231

(176)

2.0*

aatt

2634

(89)

357

(136)

1.5*

taat

2697

(91)

227

(173)

1.9*

taaa

3895

(133)

516

(198)

1.5*

taaa

3895

(133)

325

(250)

1.9*

ttaa

3376

(114)

447

(170)

1.5*

aata

3419

(117)

278

(214)

1.8*

aata

3419

(117)

445

(171)

1.5*

ttaa

3376

(114)

274

(209)

1.8*

atat

3022

(102)

392

(149)

1.5*

atat

3022

(102)

238

(182)

1.8*

taat

2697

(91)

349

(133)

1.5*

attt

3890

(131)

306

(231)

1.8*

ttat

3146

(106)

406

(154)

1.5*

ttat

3146

(106)

247

(187)

1.8*

attt

3890

(131)

495

(187)

1.4*

ttta

3895

(131)

296

(224)

1.7*

ctaa

1172

(63)

147

(88)

1.4*

atta

2697

(91)

203

(155)

1.7*

atta

2697

(91)

337

(129)

1.4*

tatt

3419

(115)

249

(188)

1.6*

tatt

3419

(115)

426

(161)

1.4*

aaaa

6731

(232)

480

(372)

1.6*

ttta

3895

(131)

482

(182)

1.4*

aaat

3890

(133)

272

(209)

1.6*

aaaa

6731

(232)

828

(321)

1.4*

WSSV (4-mer motif)

tata

2630

(60)

164

(128)

2.2*

tata

2630

(60)

290

(117)

2.0*

ataa ^j

3431

(74)

201

(150)

2.0*

ataa ^j

3431

(74)

327

(126)

1.7*

taaa

3538

(77)

195

(146)

1.9*

accc

1333

(88)

127

(148)

1.7*

aacc

1774

(79)

92

(142)

1.8*

taaa

3538

(77)

333

(128)

1.7*

aaaa

6450

(134)

330

(236)

1.8*

aaaa

6450

(134)

570

(210)

1.6*

accc

1333

(88)

68

(154)

1.8*

ccgg

374

(36)

33

(56)

1.6*

accg

699

(46)

33

(75)

1.6*

cccc

1348

(130)

118

(202)

1.6*

tacc

1424

(67)

64

(103)

1.5

cacg

995

(65)

86

(100)

1.5*

caac

2792

(125)

123

(190)

1.5

aacc

1774

(79)

150

(119)

1.5*

aata

4104

(89)

179

(134)

1.5

accg

699

(46)

56

(65)

1.4

tttt

6450

(160)

281

(240)

1.5

taac^j

1888

(60)

151

(85)

1.4

taac^j

1888

(60)

82

(90)

1.5

gtaa

1810

(58)

144

(81)

1.4

cccg

583

(56)

25

(83)

1.5

taag

1402

(45)

109

(61)

1.4

ccgg

374

(36)

16

(53)

1.5

gggt

1333

(91)

103

(124)

1.4

ccgt

940

(64)

40

(94)

1.5

tttt

6450

(160)

491

(216)

1.3

WSSV (5-mer motif)

ccggg

66

(31)

7

(116)

3.8*

tataa

760

(57)

113

(151)

2.6*

tataa

760

(57)

73

(195)

3.4*

ccccc

292

(137)

41

(342)

2.5*

cccgg

66

(31)

6

(99)

3.2*

atata

716

(54)

95

(127)

2.4*

ataaa

1202

(87)

103

(263)

3.0*

ataaa

1202

(87)

147

(188)

2.2*

taaaa

1378

(99)

102

(261)

2.6*

ccggg

66

(31)

8

(66)

2.1*

aaccg

203

(44)

15

(116)

2.6*

taaaa

1378

(99)

167

(213)

2.1*

gtata

609

(67)

45

(176)

2.6*

gtata

609

(67)

73

(143)

2.1*

atata

716

(54)

51

(136)

2.5*

aaccg

203

(44)

23

(89)

2.0*

taccc

331

(75)

22

(178)

2.4*

aaaaa

2054

(142)

231

(283)

2.0*

acccg

138

(44)

9

(102)

2.3*

tatat

716

(56)

79

(110)

2.0*

aaaaa

2054

(142)

133

(325)

2.3*

acccc

320

(103)

35

(199)

1.9*

aacca

644

(96)

41

(216)

2.3*

accgg

120

(38)

13

(73)

1.9*

ccgta

208.0

(47)

13

(105)

2.2*

cccgg

66

(31)

7

(58)

1.9*

gacct

257

(58)

16

(129)

2.2*

ctcac^k

284

(65)

30

(121)

1.9*

cgtcg

178

(59)

11

(130)

2.2*

taccc

331

(75)

34

(137)

1.8*