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Table 7 Most frequently selected genes for the BRN14 dataset.

From: Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass gene expression data

Rank Annotation Remarks Group
1 FLJ20624 **hypothetical protein FLJ20624 Gene #2 in the BRN dataset (Table 6) 1
2 M6PR mannose-6-phosphate receptor (cation dependent) Gene #6 in the BRN dataset (Table 6) 1
3 PAX8 paired box gene 8 Gene #13 in the BRN dataset (Table 6) M
4 DMXL1 Dmx-like 1 Gene #3 in the BRN dataset (Table 6) 4
5 PLG plasminogen Gene #7 in the BRN dataset (Table 6) M
6 LGALS4 lectin, galactoside-binding, soluble, 4 (galectin 4) Gene #21 in the BRN dataset (Table 6) M
7 APCS amyloid P component, serum Gene #14 in the BRN dataset (Table 6) 4
8 GATA3 GATA-binding protein 3 Verified as marker for breast cancer in [12], also identified as marker for bladder cancer class in [12] M
9 TACSTD1 tumor-associated calcium signal transducer 1 Gene #5 in the BRN dataset (Table 6) M
10 FGA fibrinogen, A alpha polypeptide Gene #10 in the BRN dataset (Table 6) 1
11 FABP1 fatty acid binding protein 1, liver Gene #17 in the BRN dataset (Table 6) M
12 SORD sorbitol dehydrogenase Gene #9 in the BRN dataset (Table 6) 2
13 EST Unknown sequence 4
14 DDOST dolichyl-diphosphooligosaccharide-protein glycosyltransferase Identified as marker for testis cancer class in [12] M
15 ITIH3 pre-alpha (globulin) inhibitor, H3 polypeptide Gene #19 in the BRN dataset (Table 6) 2
16 KIAA0128 KIAA0128 protein; septin 2 Up-regulated in renal cell carcinoma [46] 1
17 BCL6 B-cell CLL/lymphoma 6 (zinc finger protein 51) Gene #11 in the BRN dataset (Table 6) 1
18 AMD1 S-adenosylmethionine decarboxylase 1 Gene #16 in the BRN dataset (Table 6) 1
19 SERPINC1 serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 Controls expression of oncogene for hepatocarcinoma [47] 1
20 APOH apolipoprotein H (beta-2-glycoprotein I) Gene #12 in the BRN dataset (Table 6) M
21 HLCS holocarboxylase synthetase (biotin- [proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) Gene #18 in the BRN dataset (Table 6) 4
22 QKI homolog of mouse quaking QKI (KH domain RNA binding protein) Gene #24 in the BRN dataset (Table 6) 3
23 Homo sapiens mRNA for putative nuclear protein (ORF1-FL49) Expressed in spinal cord (high tissue-specificity) 3
24 GRHPR glyoxylate reductase/hydroxypyruvate reductase One of the partners of the BCL6 (see Gene #11 in Table 6) translocation in follicular lymphoma, which leads to higher risk of transformation into aggressive lymphoma [48] 1
25 HELO1 homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 Gene #22 in the BRN dataset (Table 6) 3
  1. Top 25 genes ranked from the most frequently selected genes for the BRN14 dataset. Group M: identified as a marker or repressor of a specific tumor type in originating study. Group 1: identified as a marker or repressor of a specific tumor type in other studies. Group 2: known to either promote or inhibit tumor in general. Group 3: tissue-specific genes. Group 4: unknown sequences and genes with either still-unidentified function or general housekeeping roles.