Table 7 Most frequently selected genes for the BRN14 dataset.
Rank | Annotation | Remarks | Group |
|---|---|---|---|
1 | FLJ20624 **hypothetical protein FLJ20624 | Gene #2 in the BRN dataset (Table 6) | 1 |
2 | M6PR mannose-6-phosphate receptor (cation dependent) | Gene #6 in the BRN dataset (Table 6) | 1 |
3 | PAX8 paired box gene 8 | Gene #13 in the BRN dataset (Table 6) | M |
4 | DMXL1 Dmx-like 1 | Gene #3 in the BRN dataset (Table 6) | 4 |
5 | PLG plasminogen | Gene #7 in the BRN dataset (Table 6) | M |
6 | LGALS4 lectin, galactoside-binding, soluble, 4 (galectin 4) | Gene #21 in the BRN dataset (Table 6) | M |
7 | APCS amyloid P component, serum | Gene #14 in the BRN dataset (Table 6) | 4 |
8 | GATA3 GATA-binding protein 3 | Verified as marker for breast cancer in [12], also identified as marker for bladder cancer class in [12] | M |
9 | TACSTD1 tumor-associated calcium signal transducer 1 | Gene #5 in the BRN dataset (Table 6) | M |
10 | FGA fibrinogen, A alpha polypeptide | Gene #10 in the BRN dataset (Table 6) | 1 |
11 | FABP1 fatty acid binding protein 1, liver | Gene #17 in the BRN dataset (Table 6) | M |
12 | SORD sorbitol dehydrogenase | Gene #9 in the BRN dataset (Table 6) | 2 |
13 | EST | Unknown sequence | 4 |
14 | DDOST dolichyl-diphosphooligosaccharide-protein glycosyltransferase | Identified as marker for testis cancer class in [12] | M |
15 | ITIH3 pre-alpha (globulin) inhibitor, H3 polypeptide | Gene #19 in the BRN dataset (Table 6) | 2 |
16 | KIAA0128 KIAA0128 protein; septin 2 | Up-regulated in renal cell carcinoma [46] | 1 |
17 | BCL6 B-cell CLL/lymphoma 6 (zinc finger protein 51) | Gene #11 in the BRN dataset (Table 6) | 1 |
18 | AMD1 S-adenosylmethionine decarboxylase 1 | Gene #16 in the BRN dataset (Table 6) | 1 |
19 | SERPINC1 serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 | Controls expression of oncogene for hepatocarcinoma [47] | 1 |
20 | APOH apolipoprotein H (beta-2-glycoprotein I) | Gene #12 in the BRN dataset (Table 6) | M |
21 | HLCS holocarboxylase synthetase (biotin- [proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) | Gene #18 in the BRN dataset (Table 6) | 4 |
22 | QKI homolog of mouse quaking QKI (KH domain RNA binding protein) | Gene #24 in the BRN dataset (Table 6) | 3 |
23 | Homo sapiens mRNA for putative nuclear protein (ORF1-FL49) | Expressed in spinal cord (high tissue-specificity) | 3 |
24 | GRHPR glyoxylate reductase/hydroxypyruvate reductase | One of the partners of the BCL6 (see Gene #11 in Table 6) translocation in follicular lymphoma, which leads to higher risk of transformation into aggressive lymphoma [48] | 1 |
25 | HELO1 homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 | Gene #22 in the BRN dataset (Table 6) | 3 |