Skip to main content

Table 8 Most frequently selected genes for the GCM dataset.

From: Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass gene expression data

Rank

Annotation

Remarks

Group

1

Human DNA sequence from clone 753P9 on chromosome Xq25-26.1. Contains the gene coding for Aminopeptidase P (EC 3.4.11.9, XAA-Pro/X-Pro/Proline/Aminoacylproline Aminopeptidase) and a novel gene.

Ranked #31 in the OVA marker list for the lymphoma class in [2]

M

2

Antigen, Prostate Specific, Alt. Splice Form 2

Ranked #8 in the OVA marker list for the prostate cancer class in [2]

M

3

Galectin-4

Ranked #1 in the OVA marker list for the colorectal cancer class in [2]

M

4

Homo sapiens mRNA for APCL protein, complete cds

Under-expressed in ovarian cancer, and thus a potential tumor suppressor gene in ovarian cancer [50]

1

5

Ins(1,3,4,5)P4-binding protein

Ranked #24 in the OVA marker list for the leukemia class in [2]

M

6

CARCINOEMBRYONIC ANTIGEN PRECURSOR

Ranked #4 in the OVA marker list for the colorectal cancer class in [2]

M

7

PMEL 17 PROTEIN PRECURSOR

Ranked #6 in the OVA marker list for the melanoma class in [2]

M

8

KLK1 Kallikrein 1 (renal/pancreas/salivary)

Ranked #18 in the OVA marker list for the prostate cancer class in [2]

M

9

EST: zt56g08.s1 Soares ovary tumor NbHOT Homo sapiens cDNA clone 726398 3', mRNA sequence. (from Genbank)

Ranked #5 in the OVA marker list for the mesothelioma class in [2]

M

10

EST: zr71g09.s1 Soares NhHMPu S1 Homo sapiens cDNA clone 668896 3', mRNA sequence. (from Genbank)

Ranked #5 in the OVA marker list for the CNS tumor class in [2]

M

11

Ribosomal protein S19

Ranked #1 in the OVA marker list for the lymphoma class in [2]

M

12

PULMONARY SURFACTANT-ASSOCIATED PROTEIN B PRECURSOR

Ranked #3 in the OVA marker list for the lung cancer class in [2]

M

13

Mammaglobin 2

A marker for breast cancer [51]

1

14

MRJ gene for a member of the DNAJ protein family

Associated with a tumor-transforming gene protein [52]

2

15

LPAP gene

Its product mediates proliferative and/or morphologic effects on ovarian cancer cells [53]

1

16

EST: zq49c07.s1 Stratagene hNT neuron (#937233) Homo sapiens cDNA clone 633036 3', mRNA sequence. (from Genbank)

Identified as a marker of CNS tumor in [54]

1

17

Eyes absent homolog (Eab1) mRNA

Up-regulated in epithelial ovarian cancer [55]

1

18

Pulmonary surfactant-associated protein SP-A (SFTP1) gene

Ranked #1 in the OVA marker list for the lung cancer class in [2]

M

19

EST: ab17g09.s1 Stratagene lung (#937210) Homo sapiens cDNA clone 841120 3' similar to contains LTR7.b2 LTR7 repetitive element ;, mRNA sequence. (from Genbank)

Ranked #10 in the OVA marker list for the lung cancer class in [2]

M

20

TUMOR-ASSOCIATED ANTIGEN CO-029

Ranked #5 in the OVA marker list for the colorectal cancer class in [2]

M

21

MLANA Differentiation antigen melan-A

Ranked #4 in the OVA marker list for the melanoma class in [2]

M

22

LI-cadherin

Ranked #3 in the OVA marker list for the colorectal cancer class in [2]

M

23

Antigen, Prostate Specific, Alt. Splice Form 3

Ranked #39 in the OVA marker list for the prostate cancer class in [2]

M

24

GPX2 Glutathione peroxidase 2, gastrointestinal

Found to play a role in colon cancer resistance [56]

1

25

Phosphodiesterase 9A

Ranked #28 in the OVA marker list for the prostate cancer class in [2]

M

  1. Top 25 genes ranked from the most frequently selected genes for the GCM dataset. Group M: identified as a marker or repressor of a specific tumor type in originating study. Group 1: identified as a marker or repressor of a specific tumor type in other studies. Group 2: known to either promote or inhibit tumor in general. Group 3: tissue-specific genes. Group 4: unknown sequences and genes with either still-unidentified function or general housekeeping roles.