Figure 1
From: Novel knowledge-based mean force potential at the profile level
The process of calculating frequency profiles and converting it into binary profiles. (a) For a given amino acid sequence, (b) the multiple sequence alignment is obtained by PSI-BLAST. (c) The frequency profile is calculated on the multiple sequence alignment and (d) transforms into a binary profile with a probability threshold. (e) A substring of amino acid combination is then obtained by collecting the binary profile with non-zero value for each position of the protein sequences.