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Figure 4 | BMC Bioinformatics

Figure 4

From: Computational expression deconvolution in a complex mammalian organ

Figure 4

Changes in cell compartment sizes following Ras activation in the mammary gland. (a) Calculated proportions of BAT, WAT, and MEC compartments in the mammary gland at the indicated days following oncogenic Ras activation in MTB/TRAS mice (mean ± SEM). Ras activation expands the epithelial compartment and decreases the adipocyte compartment. (b) Carmine-stained whole mounts (magnification 10×) and H&E-stained sections (magnification 100×) of number 3 mammary glands in MTB/TRAS mice showing changes in the sizes of cell compartments following oncogenic Ras activation similar to those predicted by deconvolution analysis.

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