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Table 4 Biological Processes regulated in mammary glands of pregnant vs. nulliparous mice. Biological Process terms significantly associated with lists of genes that were detected as differentially expressed, either before ("Pre-adj") or after ("Post-adj") adjusting for estimated changes in cell compartment sizes in the mammary gland of d18 pregnant vs. 10 wk nulliparous mice.

From: Computational expression deconvolution in a complex mammalian organ

GO term

Pre-adj

Post-adj

(a) Upregulated genes

  

   biosynthesis

X

 

   cellular biosynthesis

X

 

   establishment of localization

 

X

   establishment of protein localization

X

X

   intracellular protein transport

X

X

   intracellular transport

 

X

   localization

 

X

   macromolecule biosynthesis

X

 

   protein biosynthesis

X

 

   protein localization

X

X

   protein transport

X

X

   translation

X

 

   transport

 

X

(b) Downregulated genes

  

   carboxylic acid metabolism

X

 

   cell adhesion

X

 

   cellular lipid metabolism

X

 

   defense response

X

 

   fatty acid metabolism

X

 

   generation of precursor metabolites and energy

 

X

   immune response

X

 

   lipid metabolism

X

 

   organic acid metabolism

X

 

   response to biotic stimulus

X

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