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Figure 5 | BMC Bioinformatics

Figure 5

From: Cluster analysis of protein array results via similarity of Gene Ontology annotation

Figure 5

Silhouette plots of PAM clustering results for Snyder data set. Silhouette plots of PAM clustering results for 91 phospholipid binding proteins for GO (A) BP, (B) MF and (C) CC. Proteins assigned either the unknown term from each GO aspect (GO:0000004 biological process unknown, GO:0005554 molecular function unknown and GO:0008372 cellular component unknown) or using the evidence code Inferred from Electronic Annotation were not included in the clustering. Therefore 72 proteins were clustered in BP, 63 in MF and 78 in CC. The silhouette width for the entire set (average silhouette width, siD) is found at the top of each figure whereas the silhouette width for each cluster (siC) is found on the right-hand side of the figure with the cluster number (left of the colon) and number of proteins in each cluster (right of the colon). Each cluster is labelled with the GO annotation of the medoid, except BP cluster 7 and CC clusters 3 and 6 as the text did not fit on the figure. Each protein is represented by a bar and the width of the each bar represents the silhouette width for each protein (si). * GO annotation for BP cluster 7 is chromatin silencing [GO:0006342] and histone deacetylation [GO:0016575]. † GO annotation for CC cluster 3 is mitochondrial inner membrane [GO:0005743], integral to membrane [GO:0016021] and mitochondrial nucleoid [GO:0042645]. ‡ GO annotation for CC cluster 6 is plasma membrane [GO:0005886] and integral to membrane [GO:0016021].

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