Figure 4
From: Optimised amino acid specific weighting factors for unbound protein docking
Improvement of prediction quality (ZDOCK 2 benchmark). The light yellow bars show the percentage of complexes for which a near-native solution (RMSiCα<5Å) is found without the optimised weighting factors. The brown bars show the results after the application of the weighting factors. (A/B) for enzyme-inhibitor (C) for antibody-antigen and (D) for other complexes; (100%: 22 enzyme-inhibitor complexes, 25 antibody-antigen complexes and 22 other complexes); an enrichment of complexes with near-native structures on the lower ranks for all complex classes can be seen.