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Figure 1 | BMC Bioinformatics

Figure 1

From: PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs

Figure 1

Interaction graphs. Two interaction graphs showing potential interaction sites for a pair of non-interacting proteins (a) and a pair of interacting proteins (b). In (a), the number of corresponding short amino acid sequences between YBL090W and YGL055W, which also co-occur in the dataset of the interacting proteins, is calculated to be very low and hence no obvious picks are detected in this graph. In (b), a sharp pick with a score of 115 indicates that the two corresponding short amino acid sequences one in middle section of YBR288C (around amino acid 140) and the other at the C-terminal end of YGR261C co-occur 115 times in the dataset of the interacting protein pairs. It is therefore hypothesized that the two proteins YBR288C and YGR261C can potentially interact.

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BMC Bioinformatics

ISSN: 1471-2105

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