TY - JOUR AU - Hoffmann, Martin AU - Pohlers, Dirk AU - Koczan, Dirk AU - Thiesen, Hans-Jürgen AU - Wölfl, Stefan AU - Kinne, Raimund W. PY - 2006 DA - 2006/08/04 TI - Robust computational reconstitution – a new method for the comparative analysis of gene expression in tissues and isolated cell fractions JO - BMC Bioinformatics SP - 369 VL - 7 IS - 1 AB - Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-specific gene expression under diverse conditions is therefore a central aim of biomedical research. The present study compares gene expression profiles in whole tissues and isolated cell fractions purified from these tissues in patients with rheumatoid arthritis and osteoarthritis. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-7-369 DO - 10.1186/1471-2105-7-369 ID - Hoffmann2006 ER -