Table 3 MAD for mixing experiments 1 and 2. Pooled MAD of the computed relative mRNA proportions in mixing experiments 1 and 2 for different chip evaluation methods. The MAD is calculated with respect to the target values p M = 0.75, p F = 0.11, p N = 0.14 (mix 1) and p M = 0.86, p F = 0.11, p N = 0.03 (mix 2). 'MAS-S mean' and 'MAS-C mean' denote the means with respect to the four preceeding normalization methods. Notation according to Table 1.
Chip evaluation method | mix 1 | mix 2 | ||
|---|---|---|---|---|
lr | lr | |||
MAS-S t | 1.2 | 2.2 | 0.8 | 1.3 |
MAS-S t clr | 2.5 | 4.6 | 1.8 | 1.7 |
MAS-S t q | 3.3 | 4.3 | 1.1 | 1.1 |
MAS-S t c | 1.6 | 2.5 | 0.8 | 2.0 |
MAS-S mean | 2.2 | 3.4 | 1.1 | 1.5 |
MAS-C t | 0.6 | 1.9 | 0.5 | 1.1 |
MAS-C t clr | 2.1 | 4.7 | 0.9 | 1.8 |
MAS-C t q | 2.2 | 5.4 | 0.8 | 1.8 |
MAS-C t c | 2.0 | 1.9 | 1.2 | 1.0 |
MAS-C mean | 1.7 | 3.5 | 0.9 | 1.4 |
R.MA | 9.7 | 6.8 | 2.6 | 2.9 |
MBEI | 8.2 | 5.4 | 3.3 | 1.2 |
MBEI-GP | 6.6 | 5.2 | 1.1 | 1.0 |