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Figure 5 | BMC Bioinformatics

Figure 5

From: Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line

Figure 5

Intersection-Network. Gene interaction network derived from an intersection of the S1P- and invasion-network. This interaction network was hand drawn using gene names found in the S1P (Figure 3) and invasivity (Figure 4) networks as input vertices. In addition to the direction of the relationship shown by the arrow, the type is also depicted as text superimposed onto the arrow. The resulting graph contains several genes differentially expressed in the presence of S1P. These are shown in the red ovals. Genes directly related to matrix metalloproteinases are highlighted by the mustard-colored ovals. Key relationships describing the most direct connections between S1P and invasivity are highlighted by the bold purple arrows. The red arrow indicates that S1P induced transcription of NRG-1 in the microarray experiments.

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