TY - JOUR AU - Steuer, Ralf AU - Humburg, Peter AU - Selbig, Joachim PY - 2006 DA - 2006/08/15 TI - Validation and functional annotation of expression-based clusters based on gene ontology JO - BMC Bioinformatics SP - 380 VL - 7 IS - 1 AB - The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in the context of other available functional genomics data, such as existing bio-ontologies, has already provided substantial improvement for detecting and categorizing genes of interest. One common approach is to look for functional annotations that are significantly enriched within a group or cluster of genes, as compared to a reference group. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-7-380 DO - 10.1186/1471-2105-7-380 ID - Steuer2006 ER -