Table 1 Predicted cell cycle regulators.
From: Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
TF | Phase | Amplitude | Periodicity | Notes |
|---|---|---|---|---|
Ste12 | 318° | 0.03 | 0.26 | interacts with Mcm1 |
Mbp1 | 280° | 0.10 | 0.30 | G1/S, member of the Swi6-Mbp1 (MBF) and Swi4-Swi6-Mbp1 complexes |
Swi6 | 278° | 0.07 | 0.32 | G1/S, member of the Swi4-Swi6 (SBF), Swi6-Mbp1 (MBF), and Swi4-Swi6-Mbp1 complexes |
Swi4 | 252° | 0.07 | 0.33 | G1/S, member of the Swi4-Swi6 (SBF) and Swi4-Swi6-Mbp1 complexes |
Spt2 | 164° | 0.03 | 0.24 | interacts with both histones and SWI-SNF components |
Fkh2 | 160° | 0.04 | 0.26 | G2-specific transcription in the mitotic cell cycle, forms complex with Ndd1 and Mcm1 |
Ndd1 | 098° | 0.08 | 0.30 | late S, forms complex with Fkh2 and Mcm1 |
Bas1 | 084° | 0.02 | 0.21 | regulation of basal and induced expression of genes of the purine and histidine biosynthesis pathways |
Mcm1 | 044° | 0.03 | 0.27 | DNA replication initiation (TAS), member of Fkh2-Ndd1-Mcm1 and Mcm1-Swi5-Ace2 complexes |
Yox1 | 025° | 0.06 | 0.19 | binds to Mcm1p and Early Cell-cycle Boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 |
Swi5 | 002° | 0.06 | 0.20 | G1 and at the M/G1 boundary, forms complex with Mcm1 and Ace2 |
Ace2 | 001° | 0.05 | 0.29 | G1, forms complex with Mcm1 and Swi5 |