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Table 2 Significant TFBS of PTM subclusters from the AML data set.

From: Analysis of promoter regions of co-expressed genes identified by microarray analysis

Cluster1 Subclusters Number of genes Significant TFBS present in all promoters of a givencluster2
FOXO3A 1A 3 No significant TFBS
  1B 6 CAAT, CETS1P54, FOXO4 (FOXO1 (4/6) FOXO3 (4/6))
  1C 4 No significant TFBS
MAX 2A 12 Significant TFBS but not present in all
  2B 13 AP1, BARBIE, GATA, GATA1, HFH3, LMO2COM
SP3 3A 6 Significant TFBS but not present in all
  3B 8 No significant TFBS
  3C 5 Significant TFBS but not present in all
  3D 13 AP1, BARBIE, CAAT, CEBPDELTA, CETS1P54, FOXO4, GATA, GATA1, LMO2COM, NKX25, S8
STAT3 4A 6 MAZ, NRF2
  4B 6 AP1, GATA, GATA1, LIMO2COM
TGIF2 5A 7 Significant TFBS but not present in all
  5B 4 CETS136, ELK1, ETS1, FOXO4, GATA, GATA1, IK1, LMO2COM, NRF2, RFX1, SREBP1, TGIF, USF
  1. 1 DNA binding transcription factor used for cluster formation.
  2. 2 Significant TFBS present in all promoters of the subcluster genes and the TFBS in parenthesis are present in the fraction promoters indicated.