Figure 5

Questing the GeneLibrarian: illustrative example. For a given gene list – ABL, ATM, ATR, GADD45, PCNA, DNAPK, and TP53 – the annotation analysis result indicates that there are two distinct processes among these genes: cell cycle and DNA repair. Selecting the queried genes, GeneLibrarian extracts and summarizes related information from the literature, and users can use these summaries to expand their list for further annotation analysis. The result exhibits a group of apoptosis-related genes that users might not think about. Finally, users can enter extra terms like "apoptosis" and "tumor growth"; the system submits these genes and terms to PubMed and lists and ranks PMIDs by the number of the present terms.