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Table 2 Significance of miRNA target predictions based on miRNA microarray perturbation data.

From: miTarget: microRNA target gene prediction using a support vector machine

 

Down-regulated genes

With 3'UTR

miTarget

Common

P-values

miR-1

96

66

2,295

24

9.47E-08

miR-124a

174

117

3,048

36

1.02E-05

miR-373

65

40

2,964

15

2.62E-04

  1. The downregulated gene # is the number of genes downregulated by overexpression of each miRNA, reported in Lim's paper [40] and "With 3'UTR" indicates the number of downregulated genes with a 3'UTR sequence. The "miTarget" is the number of target gene candidates predicted by miTarget; the "Common" means the number of candidates shared by "With 3'UTR". The P-value was calculated by hypergeometric testing.
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BMC Bioinformatics

ISSN: 1471-2105

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