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Figure 3 | BMC Bioinformatics

Figure 3

From: M-GCAT: interactively and efficiently constructing large-scale multiple genome comparison frameworks in closely related species

Figure 3

The M-GCAT genome comparison workspace. The M-GCAT genome comparison workspace showing the multi-MUMs, multi-MUM clusters, global multiple alignment, gene map, and an orthologous gene between four complete bacterial sequences: Yersinia pestis biovar Mediaevails, Yersinia pestis CO92, and Yersinia pseudotuberculosis IP32953. By analyzing the visual results for this comparison we can quickly observe that these sequences are highly similar, and except for a few smaller regions, there is high sequence identity across all genomes. The green vertical rectangles represent multi-MUM clusters, and the inverted green vertical rectangles indicate regions containing large-scale rearrangements. The highlighted(light green) multi-MUM cluster is an example of a region that was aligned among all genomes. In the gene map window genes are drawn as horizontal rectangles, and all genes annotated in the corresponding PTT file will be displayed. The genes are color coded by function, and a legend is provided at the bottom for quick reference when analyzing the genomes. The vertical lines between the genes represent the multi-MUMs found during comparison.

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