Skip to main content

Table 5 Most abundant GO terms for {Q(X)n} CB regions in the fruitfly, mouse, rat and human proteomes *

From: Exhaustive assignment of compositional bias reveals universally prevalent biased regions: analysis of functional associations in human and Drosophila

Fruitfly (total = 835)

Rat (total = 234)

Mouse (total = 267)

Human (total = 335)

Number**

GO term and its description

Number**

GO term and its description

Number**

GO term and its description

Number**

GO term and its description

245

GO:0005634 ; nucleus

38

GO:0005634 ; nucleus

78

GO:0005634 ; nucleus

114

GO:0005634 ; nucleus

152

GO:0006357 ; regulation of transcription from RNA polymerase II promoter

28

GO:0006355 ; DNA-dependent regulation of transcription

49

GO:0006355 ; DNA-dependent regulation of transcription

68

GO:0006355 ; DNA-dependent regulation of transcription

137

GO:0003700 ; transcription factor activity

15

GO:0003700 ; transcription factor activity

36

GO:0005515 ; protein-binding

51

GO:0008270 ; Zinc ion binding

125

GO:0003677 ; DNA-binding

6

GO:0004871 ; signal transducer activity

31

GO:0003677 ; DNA-binding

39

GO:0003700 ; transcription factor activity

99

GO:0005515 ; protein-binding

4

GO:0030216 ; keratinocyte differentiation

28

GO:0008270 ; Zinc ion binding

35

GO:0003677 ; DNA-binding

92

GO:0008270 ; Zinc ion binding

4

GO:0001533 ; cornified envelope

25

GO:0003700 ; transcription factor activity

24

GO:0003676 ; nucleic acid binding

78

GO:0006355 ; DNA-dependent regulation of transcription

  

21

GO:0005737 ; cytoplasm

21

GO:0046872 ; metal-ion binding

62

GO:0005737 ; cytoplasm

  

12

GO:0006350 ; transcription

20

GO:0003713 ; transcriptional coactivator activity

61

GO:0007498 ; mesoderm development

  

9

GO:0045944 ; positive regulation of transcription from RNA pol II promoter

17

GO:0006350 ; transcription

59

GO:0003677 ; RNA polymerase II transcription factor activity

  

9

GO:0003713 ; transcription coactivator activity

11

GO:0006366 ; transcription from RNA pol II promoter

57

GO:0003729 ; mRNA binding

  

5

GO:00016564 ; transcriptional repressor activity

11

GO:0004871 ; signal transducer activity

53

GO:0045449 ; regulation of transcription

  

5

GO:00016563 ; transcriptional activator activity

10

GO:00016563 ; transcriptional activator activity

47

GO:0009993 ; oogenesis (sensu insecta)

    

8

GO:0003702 ; RNA pol II transcription factor activity

47

GO:0007398 ; ectoderm development

    

6

GO:0006367 ; Transcription initiation from RNA pol II promoter

47

GO:0003704 ; specific RNA polymerase II transcription factor activity

      

43

GO:0030528 ; transcription regulatory activity

      

41

GO:0008283 ; cell proliferation

      

36

GO:0003779 ; actin binding

      

32

GO:0007476 ; wing morphogenesis

      

30

GO:0007242 ; intracellular signaling cascade

      
  1. * GO terms common to all four organisms are in bold. Other terms directly associated with 'transcription' or 'nucleic acids' are in italics.
  2. ** Number of occurrences of each GO term. For each proteome, the GO terms are sorted in decreasing order of abundance.