Figure 5

Optimized solution spaces for biomass and lysine synthesis rates in C. glutamicum for varying ammonia and oxygen uptake rates. The uptake rate of glucose was fixed at 100 moles/Lh. The choice of the objective function was maximization of lysine. a shows the biomass synthesis rates at various ammonia and oxygen consumption rates. The numbered points represent, 1: (146, 91, 124) 2: (155, 127, 0); 3: (365, 67, 0); 4: (220, 40, 0); in the order given by oxygen and ammonia uptake rates and biomass formation rate, respectively. b shows the lysine synthesis rates at various ammonia and oxygen consumption rates. The numbered points indicate, 1: (146, 91, 0) 2: (155, 127, 63.5); 3: (365, 67, 33.5); 4: (220, 40, 20); in the order given by oxygen and ammonia uptake rates and biomass formation rate respectively. '○' indicates experimental data at 11.5 h; '□' indicates experimental data at 13.5 h and '△'indicates experimental data at 15.8 h.